WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_CTTTGT_V$LEF1_Q2       ID:DB_ID:2428
C=1939; O=13; E=2.07; R=6.29; rawP=7.46e-08; adjP=9.47e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
3  ENSG00000109790 NA KLHL5 kelch-like 5 (Drosophila) 51088 ENSG00000109790
4  ENSG00000046889 NA PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 80243 ENSG00000046889
5  ENSG00000127920 NA GNG11 guanine nucleotide binding protein (G protein), gamma 11 2791 ENSG00000127920
6  ENSG00000145555 NA MYO10 myosin X 4651 ENSG00000145555
7  ENSG00000179776 NA CDH5 cadherin 5, type 2 (vascular endothelium) 1003 ENSG00000179776
8  ENSG00000163362 NA C1orf106 chromosome 1 open reading frame 106 55765 ENSG00000163362
9  ENSG00000183688 NA FAM101B family with sequence similarity 101, member B 359845 ENSG00000183688
10  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
11  ENSG00000118292 NA C1orf54 chromosome 1 open reading frame 54 79630 ENSG00000118292
12  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878
13  ENSG00000176641 NA RNF152 ring finger protein 152 220441 ENSG00000176641


Database:Transcription Target       Name:hsa_V$NKX61_01       ID:DB_ID:2090
C=236; O=6; E=0.25; R=23.84; rawP=1.97e-07; adjP=1.25e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000124766 NA SOX4 SRY (sex determining region Y)-box 4 6659 ENSG00000124766
2  ENSG00000109790 NA KLHL5 kelch-like 5 (Drosophila) 51088 ENSG00000109790
3  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
4  ENSG00000145555 NA MYO10 myosin X 4651 ENSG00000145555
5  ENSG00000196628 NA TCF4 transcription factor 4 6925 ENSG00000196628
6  ENSG00000176641 NA RNF152 ring finger protein 152 220441 ENSG00000176641


Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=11; E=1.98; R=5.55; rawP=3.06e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
3  ENSG00000196628 NA TCF4 transcription factor 4 6925 ENSG00000196628
4  ENSG00000179776 NA CDH5 cadherin 5, type 2 (vascular endothelium) 1003 ENSG00000179776
5  ENSG00000167210 NA LOXHD1 lipoxygenase homology domains 1 125336 ENSG00000167210
6  ENSG00000213949 NA ITGA1 integrin, alpha 1 3672 ENSG00000213949
7  ENSG00000124766 NA SOX4 SRY (sex determining region Y)-box 4 6659 ENSG00000124766
8  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
9  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
10  ENSG00000164035 NA EMCN endomucin 51705 ENSG00000164035
11  ENSG00000176641 NA RNF152 ring finger protein 152 220441 ENSG00000176641


Database:Transcription Target       Name:hsa_TGCCAAR_V$NF1_Q6       ID:DB_ID:2436
C=709; O=7; E=0.76; R=9.26; rawP=9.66e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000124766 NA SOX4 SRY (sex determining region Y)-box 4 6659 ENSG00000124766
2  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
3  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
4  ENSG00000037280 NA FLT4 fms-related tyrosine kinase 4 2324 ENSG00000037280
5  ENSG00000196628 NA TCF4 transcription factor 4 6925 ENSG00000196628
6  ENSG00000164035 NA EMCN endomucin 51705 ENSG00000164035
7  ENSG00000164284 NA GRPEL2 GrpE-like 2, mitochondrial (E. coli) 134266 ENSG00000164284


Database:Transcription Target       Name:hsa_V$NFAT_Q6       ID:DB_ID:2050
C=245; O=5; E=0.26; R=19.13; rawP=6.44e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
2  ENSG00000147113 NA CXorf36 chromosome X open reading frame 36 79742 ENSG00000147113
3  ENSG00000046889 NA PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 80243 ENSG00000046889
4  ENSG00000113555 NA PCDH12 protocadherin 12 51294 ENSG00000113555
5  ENSG00000037280 NA FLT4 fms-related tyrosine kinase 4 2324 ENSG00000037280


Database:Transcription Target       Name:hsa_RYTTCCTG_V$ETS2_B       ID:DB_ID:2415
C=1074; O=8; E=1.15; R=6.98; rawP=1.62e-05; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
2  ENSG00000174327 NA SLC16A13 solute carrier family 16, member 13 (monocarboxylic acid transporter 13) 201232 ENSG00000174327
3  ENSG00000127920 NA GNG11 guanine nucleotide binding protein (G protein), gamma 11 2791 ENSG00000127920
4  ENSG00000145555 NA MYO10 myosin X 4651 ENSG00000145555
5  ENSG00000179776 NA CDH5 cadherin 5, type 2 (vascular endothelium) 1003 ENSG00000179776
6  ENSG00000213949 NA ITGA1 integrin, alpha 1 3672 ENSG00000213949
7  ENSG00000130816 NA DNMT1 DNA (cytosine-5-)-methyltransferase 1 1786 ENSG00000130816
8  ENSG00000176641 NA RNF152 ring finger protein 152 220441 ENSG00000176641


Database:Transcription Target       Name:hsa_TGGAAA_V$NFAT_Q4_01       ID:DB_ID:2437
C=1871; O=10; E=2.00; R=5.01; rawP=2.25e-05; adjP=0.0004
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
2  ENSG00000147113 NA CXorf36 chromosome X open reading frame 36 79742 ENSG00000147113
3  ENSG00000196628 NA TCF4 transcription factor 4 6925 ENSG00000196628
4  ENSG00000179776 NA CDH5 cadherin 5, type 2 (vascular endothelium) 1003 ENSG00000179776
5  ENSG00000152128 NA TMEM163 transmembrane protein 163 81615 ENSG00000152128
6  ENSG00000138316 NA ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 140766 ENSG00000138316
7  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
8  ENSG00000113555 NA PCDH12 protocadherin 12 51294 ENSG00000113555
9  ENSG00000196878 NA LAMB3 laminin, beta 3 3914 ENSG00000196878
10  ENSG00000176641 NA RNF152 ring finger protein 152 220441 ENSG00000176641


Database:Transcription Target       Name:hsa_V$P53_02       ID:DB_ID:2033
C=248; O=4; E=0.26; R=15.12; rawP=0.0001; adjP=0.0016
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
2  ENSG00000124766 NA SOX4 SRY (sex determining region Y)-box 4 6659 ENSG00000124766
3  ENSG00000046889 NA PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 80243 ENSG00000046889
4  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=10; E=2.61; R=3.83; rawP=0.0002; adjP=0.0023
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112769 NA LAMA4 laminin, alpha 4 3910 ENSG00000112769
2  ENSG00000111145 NA ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 2004 ENSG00000111145
3  ENSG00000147113 NA CXorf36 chromosome X open reading frame 36 79742 ENSG00000147113
4  ENSG00000091409 NA ITGA6 integrin, alpha 6 3655 ENSG00000091409
5  ENSG00000196460 NA RFX8 regulatory factor X, 8 731220 ENSG00000196460
6  ENSG00000124766 NA SOX4 SRY (sex determining region Y)-box 4 6659 ENSG00000124766
7  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
8  ENSG00000157404 NA KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 3815 ENSG00000157404
9  ENSG00000164284 NA GRPEL2 GrpE-like 2, mitochondrial (E. coli) 134266 ENSG00000164284
10  ENSG00000176641 NA RNF152 ring finger protein 152 220441 ENSG00000176641


Database:Transcription Target       Name:hsa_V$SOX5_01       ID:DB_ID:1868
C=261; O=4; E=0.28; R=14.37; rawP=0.0002; adjP=0.0023
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000046889 NA PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 80243 ENSG00000046889
2  ENSG00000182621 NA PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 23236 ENSG00000182621
3  ENSG00000196628 NA TCF4 transcription factor 4 6925 ENSG00000196628
4  ENSG00000164035 NA EMCN endomucin 51705 ENSG00000164035




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).